Lorentz Center - Lorentz Center Highlights
  Current Workshop  |   Overview   Back  |   Print   |   Home   |   Search   |     

    Lorentz Center Highlights

Steve Gross (University of California, Irvine)

'Moving cargos in a cell: how do molecular motors work together?'

ABSTRACT: Cells are highly organized, and create and maintain much of this organization through the use of active transport. I will introduce the molecular motors that are used for such active transport, and discuss methods of understanding how the motor's activity is controlled to provide useful transport. Starting with illustrating the transport by looking inside of cells, we will then transition to the function of single motors, to see what aspects of transport can be understood from single-molecule studies. Finding inconsistancies between single-molecule function and what goes on in the cell, we will discuss how to build complexity in a controlled manner, to better understand how multiple motors working together can lead to the sort of function observed in cells.