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Jeroen Raes

VIB Department of Molecular and Cellular Interactions, Vrije Universiteit Brussel, Belgium

"Untangling microbial ecosystems using metagenomics: from the oceans to human disease"

ABSTRACT: Metagenomics allows a large-scale, unbiased insight in the functional and phylogenetic composition of complex microbial communities. However, given the complexity of these data, computational analysis is a major bottleneck. Here, I will discuss our experiences in developing methods for the analysis of metagenomics data and their application in eg. the global ocean and human-associated communities (the human microbiome) such as the intestinal tract. These approaches should lead the way towards an 'eco-systems biology' approach to the study of microbial communities and provide great opportunities for the study of the role of commensals in human disease.